Covid-19-vaccination

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Revision as of 23:37, 31 January 2022 by Laura (talk | contribs) (End of the simulation)
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Problem definition

Currently, there is a new wave of infection in the COVID-19 pandemic with high number of infections. In Germany, for example, more than 50,000 new infections are currently reported every day. To reduce the infection rate, a wide variety of measures have been implemented. One of these measures are the vaccination and masks. Vaccination can reduce the risk of infection and the likelihood of transmissibility. A simulation is conducted to vividly identify the extent to which vaccination could contain the pandemic.

Method

The purpose of the simulation is to show how COVID-19 vaccination affects the spread of the pandemic. I will use an agent-based model, this method enables to reflect the real scenario at the best. Thereby people can be represented by autonomous agents and it is possible to simulate their daily behavior and thus the spread of the virus in a simplified way.


Model

The model shows people in a village. The inhabitants move freely in their village, reflecting their everyday behavior. To simulate the spread of Covid-19, a certain proportion of the population is already unknowingly infected at the beginning of the simulation. As the simulation progresses, they infect their fellow villagers with the virus, allowing it to spread throughout the village. Some of the people are vaccinated. How many among the people are vaccinated defines the particular vaccination rate. Vaccination in this model reduces the risk of infection of a person. To analyze the impact of vaccination on the spread of the pandemic. Several simulations with different vaccination rates are run and their results are compared.

Environment

The model represents an exemplary village in Germany with 1605 inhabitants where the Covid-19 virus is spreaded. For simplification, the village is closed that is new people cannot come in and people of the village cannot go out.

Agents

The people are represented by agents, which have colored blue and have the "people" shape. As mentioned above, a part of the population defined by the vaccination-rate is vaccinated. This property is randomly assigned to the inhabitants. Vaccinated individuals are marked in green. For simplicity, the simulations do not distinguish between different vaccination statuses (1st, 2nd, or 3rd vaccination). In the following, the vaccination rate and the corresponding numbers of the parameters refer to a "complete" vaccination status, i.e. citizens have already received 2 vaccinations.

Movement

People move in a certain radius [mobility] randomly in their environment, this reflects in a very simplified way the behavior of people and their encounters with other people in everyday life, for example, people's way to work, shopping, going to restaurants, etc.

Spread of infection

The initially infected people (marked red or orange in the model) [infected-people] can infect other healthy people with a defined probability if they are in their vicinity. The probability of being infected, i.e. the risk of infection of a person depends on whether he is vaccinated [infection-risk-vac] or unvaccinated [infection-risk-unvac]. The risk of infection is significantly lower for vaccinated individuals, so the likelihood of being infected by a person is lower. Once the person is infected, their color changes. Infected vaccinated persons turn orange and infected unvaccinated persons turn red. For simplification, we do not take into account the incubation period or the time spent with an infected person. In addition, other measures can be set, which are intended to protect against the virus by reducing the risk of infection. These are wearing a mask and social distancing, these parameters are explained in more detail below. If a person is infected, he or she goes into quarantine with a certain probability. This is simulated in the model in a simplified way, in that the person still moves freely, but can infect other people with a lower probability [quarantine-rate]. After the recovery time [recovery-time], the previously infected person is immune (indicated by the color gray) to the virus [immunity-possibility]. This means that they cannot be infected again. Since infected persons can also die from Covid-19 in the worst case, this is also taken into account in the mortality rate. The mortality rate [mortality-rate] indicates how many of the infected die. Dead persons are marked with an "x".

End of the simulation

The simulation ends when the Covid-19 virus is eradicated from the model village. This means that no more people are infected. This can happen when everyone is immune or so many or so few are infected that the risk of infection approaches 0.

Parameter

Essential model parameter

Infected people at the beginning


Vaccination rate


Risk of infection of unvaccinated people


Risk of infection of vaccinated people


Mobility


Ricovery time


Possibility of mobility


Mortality rate


Further measures for reducing the risk of infection

Masks


Social Distancing


Quarantine

Output

Monitors

Plots

Results

Conclusion

Sources

NetLogo File